Shrimp White Spot Syndrome - from Pathology to Pathogenomics

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2009Publisher:The Japanese Society of Fish PathologyJournal:Fish Pathology, volume 44, pages 55-58 (issn: 0388-788X, eissn: 1881-7335,

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Authors: Kuan Fu Liu; Wang-Jing Liu; Guang-Hsiung Kou; Chu-Fang Lo;

doi: 10.3147/jsfp.44.55

Shrimp White Spot Syndrome - from Pathology to Pathogenomics

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Abstract

For shrimp with low-level white spot syndrome virus (WSSV, = PRDV) infection, environmental or physiological stresses can trigger replication of the virus and lead to a full-blown outbreak of white spot disease. This review will describe how pathogenomic studies have revealed some of the mechanisms that underlie this aspect of WSSV pathology. In the model that emerges, stressors activate shrimp STAT (signal transducer and activator of transcription), which is then annexed by the virus and used to activate the promoter of the immediate early gene WSSV ie1. This in turn leads to rapid replication of the virus.

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National Taiwan University of Arts
Taiwan

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