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Article . 2021 . Peer-reviewed
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Karadeniz Fen Bilimleri Dergisi
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Rheum ribes Özütlerinin Antioksidan ve Antibakteriyel Aktiviteleri

Authors: Hatice Aysun MERCİMEK TAKCI; Filiz UÇAN TÜRKMEN; Mustafa GÜNEŞ; Pemra BAKIRHAN;

Rheum ribes Özütlerinin Antioksidan ve Antibakteriyel Aktiviteleri

Abstract

Polygonaceae familyasının türü olan Rheum ribes’in taze gövde ve yaprakları Lübnan, İran ve Türkiye’nin doğusunda sebze olarak tüketilmektedir. Son zamanlarda farmakolojik alanlarda kullanılan bu bitkiden Asya ülkelerinde saf ilaç materyalleri üretilmektedir. Çalışmamızda, Rheum ribes gövde kısımlarından etil asetat, hekzan, metanol ve saf su çözücüleri kullanılarak 10-100 mg/mL konsantrasyonlarda hazırlanan özütlerin in vitro fitokimyasal, antioksidan ve antibakteriyel aktiviteleri incelenmiştir. Çözücülere bağlı olarak ekstraksiyon verimi değişmekle birlikte en yüksek ekstraksiyon verimi (%25.3), en yüksek total fenolik (0.80±0.00 mg GAE/g) ve flavonoid içerik (0.321±0.00 mg RE/g) 100 mg/mL konsantrasyonda metanol özütünde belirlenmiştir. Rheum ribes metanol gövde özütünün DPPH· süpürme aktivitesi %91.10±0.51 olarak kaydedilmiş olup IC50 dozu 10.50 mg/mL’dir. En yüksek Fe(II) iyonlarını şelatlama aktivitesi %49.70±3.10, indirgeme kapasitesi (0.19±0.00) ve süperoksit anyonu giderme aktivitesi (%39.20±2.40) 100 mg/mL konsantrasyonda metanol özütünde belirlenmiştir. Rheum ribes’in etil asetat, hekzan ve metanol özütlerinin test bakterileri üzerinde antibakteriyel aktivite gösteremediği belirlenmiştir. Saf su özütünün gösterdiği antibakteriyel aktivite 9.00±1.00 ve 14.50±1.50 mm zon çapı aralığındadır. En yüksek inhibitör etki 14.50±1.50 mm zon çapı ile S. aureus’a karşı gözlenmiştir. 

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
3
Top 10%
Average
Average
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