Abstract A computer program for the simulation of polymer plastication in screw injection molding machine created on basis of the theoretical model presented in part 1 of this paper is discussed. As simulation examples various process characteristics, e. g. solid bed, pressure and temperature profiles, are computed using the material parameters for high density polyethylene and three-zones-screw of diameter 20 mm. Effects of different geometric and operating parameters on plastication course are also demonstrated. Simulation results with respect to the screw rotation time are compared with experimental data measured for low density polyethylene, polypropylene, polystyrene, polyoxymethylene and polyamide 6. It was found that the computer program reflects correctly all features of a true plasticating system in injection molding machine. It provides also good agreement of model predictions with experimental data.