This paper presents a predicted path loss model based on path profile in suburban Vehicle-to-Infrastructure propagation environments for 433MHz Sub-GHz band. Effecting of path profile parameters (Received Signal Strength, Tx-Rx antenna heights, Tx-Rx separating distance, Spreading Factor, Bandwidth, and coding rate) on link quality is considered as a crucial matter to maintain link availability at maximum path loss. The proposed model is based on the log-distance path loss model for line-of-sight propagation scenario. The path loss model is constructed based on the polynomial regression approach. This paper uses the principal of weighted product model to estimate the optimal path profile parameters which provide an optimum path loss.