Autobiographical memory—memory for our personal past—is a multifaceted mnemonic activity that evolves throughout the lifespan and interacts with numerous other cognitive functions. Retrieving personal past events engages processes of cue specification, search, and elaboration of details within the specified event. The retrieved content varies from specific episodes unique in time and place to more general representations of autobiographical facts (personal semantics). As expected given this complexity, autobiographical memory is mediated by distributed brain networks, with key regions in the medial temporal lobes and their connections to both anterior and posterior cortical regions supporting different levels of specificity in memory retrieval. These patterns only partially overlap with those evoked by laboratory-based episodic memory paradigms. While most empirical work on autobiographical memory focuses on the recall of particular past events, more recent research concerns individual differences in the way that people tend to remember their past. The formal study of autobiographical memory dates to the 19th century, but research in this field is burgeoning, particularly in relation to brain network connectivity. New paradigms that bridge the gap between traditional laboratory memory tasks and rich, naturalistic autobiographical memories will enhance the understanding of memory as it operates in everyday life.