Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ https://doi.org/10.3...arrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
https://doi.org/10.31224/5672...
Article . 2025 . Peer-reviewed
License: CC BY
Data sources: Crossref
addClaim

Evaluating a novel Transcutaneous Auricular Vagus Nerve Stimulation control condition

Authors: Yishai Valter; Gunnar Turnquist; Kamran Nazim; Teresa J. Kimberley; Giuseppina Pilloni; Leigh Charvet; Bashar W. Badran; +1 Authors

Evaluating a novel Transcutaneous Auricular Vagus Nerve Stimulation control condition

Abstract

Objective: Transcutaneous auricular vagus nerve stimulation (taVNS) is being actively explored as a therapeutic option for multiple conditions. Current blinding strategies employed in the literature are variable, and non-optimal due to perception confounds. Additional strategies are needed. We assessed the blinding integrity of taVNS when used with a novel sham waveform. Methods: Ten healthy subjects (mean age: 36.6 ± 11.3 y) completed a randomized, double-blind, parallel study. taVNS was delivered while participants performed tasks mimicking upper limb rehabilitative training. The intervention consisted of 6, thirty-minute sessions over 2 weeks. The blinding assessment was performed after the last session. Results: Majority of the participants (n=6) were unsure of their stimulation allocation. The binomial test indicated no evidence of systematic unblinding based on guessing alone. Bang’s blinding index was -0.20 and -0.60 for the active and sham groups, respectively. Discussion: This study's sham taVNS protocol indicates satisfactory participant blinding. Testing on larger samples and clinical populations is advocated to further demonstrate utility.

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
hybrid