descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Jan 1979 English Publisher:Informa UK LimitedJournal:Immunological Communications, volume 8, pages 1-9 (issn: 0090-0877,

Authors: T. Van Zoost; H. Laltoo; L. S. Kind;

doi: 10.3109/08820137909044702

pmid: 422220

IgE Antibody Response to Mite Antigens in Mite Infested Mice

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Abstract

Mice infested at birth with the mouse mite Myocoptes musculinus developed positive skin tests to mite antigens at the age of 5 weeks. Serum IgE antibodies directed against mite antigens were first detected at 6 weeks of age and high levels of IgE were present as long as 1 year later. Similar kinetics of IgE formation were observed in mice infected as adults. Mast cell degranulation by mite extract was demonstrated in connective tissue obtained from the skin of mite infested mice.

Related Organizations

Dalhousie University
Canada

Keywords

Male, Aging, Mites, Passive Cutaneous Anaphylaxis, Immunoglobulin E, Mice, Antibody Formation, Animals, Female, Mast Cells, Antigens, Skin Tests

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