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A Seroepidemiological Study of HTLV-1 Infection in Nepal

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1992 English Publisher:Informa UK LimitedJournal:Scandinavian Journal of Infectious Diseases, volume 24, pages 399-400 (issn: 0036-5548, eissn: 1651-1980,

Authors: Takayoshi Shotake; Ken-Ichi Takayanagi; Kazuko Hirai; Isao Yuasa; Takafumi Ishida;

doi: 10.3109/00365549209061352

pmid: 1354887

A Seroepidemiological Study of HTLV-1 Infection in Nepal

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Abstract

A seroepidemiological survey of antibodies to human T-lymphotropic retrovirus type-1 (HTLV-1) was carried out among 413 residents of Chitwan, Dhapakhel and Katmandu in Nepal. Donor screening was first carried out by the gelatin particle agglutination (PA) tests and positive sera were retested by an improved PA test, indirect immunofluorescence (IF) and Western blotting (WB). Nine sera showed positive reaction in the first PA screening. Among these positive sera, 1 serum was positive in the improved PA test and the IF test but negative in the WB test. This study suggests that the prevalence of HTLV-1 in Nepalese people is negligible.

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Keywords

Cross-Sectional Studies, Nepal, Deltaretrovirus Antibodies, Seroepidemiologic Studies, Prevalence, Humans, HTLV-I Infections

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