Objective: The main objective of this study was to see the role ofHysterosalpingoscintigraphy (HSSG) in the evaluation of fallopian tube patency and function and its comparison withLaparoscopy. Design: Comparative Study. Place and Duration of Study: The study was conducted at BahawalpurInstitute of Nuclear Medicine and Radiotherapy, Bahawalpur during a period of 6 months from 1st March to 31st August2005. Material and Methods: Static HSSG was performed after instillation of 4mCi 99mTc-MAA in posterior vaginalfornix in 40 patients. Images were taken at an interval of 1hr, 2hrs, 3hrs anteriorly in supine position. Results: Out of40 patients, 20 patients had bilateral blocked tubes, 13 patients had bilateral patent tubes, 4 patients had blocked lefttube and 3 patients had blocked right tube. The calculated Sensitivity, Specificity, PPV and NPV for HSSG was 90%,85%, 90% and 90%. The agreement between Laparoscopy and HSSG was found in 36 out of 40 patients.Conclusions: This simple procedure can play an important role in the evaluation of infertility, especially in patients whosuffer from unexplained infertility due to a tubal factor. It was also concluded that HSSG be accepted with the othercorrelative imaging procedures, on a routine basis in work up of infertile females.