Abstract In accordance with Article 6 of Regulation (EC) No 396/2005, Spain, herewith referred as the evaluating Member State (EMS), received an application from Nissan Chemical Europe SARL to set new MRLs for the active substance amisulbrom in tomatoes, aubergines and lettuce. In order to accommodate for the intended uses of amisulbrom, Spain proposed to raise the existing default MRL value of 0.01* mg/kg to 0.4 mg/kg for tomatoes and aubergines, and to 5 mg/kg for lettuce. Spain drafted an evaluation report according to Article 8 of Regulation (EC) No 396/2005 which was submitted to the European Commission and forwarded to EFSA. According to EFSA the data are sufficient to derive MRL proposals of 0.4 mg/kg for the intended use of amisulbrom on tomatoes and aubergines and of 4 mg/kg for the intended use of amisulbrom on lettuce. Analytical enforcement methods are available to control the residues of amisulbrom in the crops under consideration at the LOQ of 0.01 mg/kg. Based on the risk assessment results, EFSA concludes that the proposed uses of amisulbrom in tomatoes, aubergines and lettuce in Spain will not result in consumer exposure exceeding the provisional toxicological reference values and therefore are unlikely to pose a consumer health risk. However, since the peer review process is not yet finalised, the conclusions reached in this reasoned opinion should be taken as provisional and might need to be reconsidered in the light of the outcome of the peer review.