Transcription factors and osteoblasts
Copyright policy )Transcription factors and osteoblasts
Transcription factors play a key role in determination of the fate of the cells in osteoblastic and chondrocytic lineage. A runt family member, Cbfa, is indispensable for osteoblastic differentiation. Sox 9 and scleraxis are involved in the phenotypic expression in chondrocytes and the cells of early stage connective tissues. These transcription factors will give us a clue to unravel interaction of these known and yet unknown transcription factors to fully understand the mechanisms of skeletal cells ' differentiation and regulation of their functions.
Basic Helix-Loop-Helix Proteins, Mice, Knockout, Mice, Osteoblasts, High Mobility Group Proteins, Animals, Core Binding Factor Alpha 1 Subunit, SOX9 Transcription Factor, Core Binding Factor beta Subunit, Transcription Factors
Basic Helix-Loop-Helix Proteins, Mice, Knockout, Mice, Osteoblasts, High Mobility Group Proteins, Animals, Core Binding Factor Alpha 1 Subunit, SOX9 Transcription Factor, Core Binding Factor beta Subunit, Transcription Factors
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