Protein-ligand docking
Copyright policy )Protein-ligand docking
Ligand-docking is an established computational technique universally applied in structure-based drug design. Since the first attempts carried out in the early '80s to predict the three-dimensional conformation of a protein-ligand bound complex, this methodology has evolved constantly and it is presently implemented in many different ways. The present study aims at explaining the standard protein-ligand docking protocol, together with its main advantages and drawbacks. Milestone reports and future directions are reported and discussed as well.
- Italian Institute of Technology Italy
- University of Urbino Italy
Models, Molecular, Stochastic Processes, Protein Conformation, Drug Design, Computer-Aided Design, Receptors, Cell Surface, Molecular Dynamics Simulation, Ligands, Algorithms, Protein Binding
Models, Molecular, Stochastic Processes, Protein Conformation, Drug Design, Computer-Aided Design, Receptors, Cell Surface, Molecular Dynamics Simulation, Ligands, Algorithms, Protein Binding
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).21 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!