Soluble interleukin-2 receptor in cancer
Copyright policy )Soluble interleukin-2 receptor in cancer
Levels of serum sIL-2R (soluble interleukin-2 receptor) reflect the total amount of activated T lymphocytes in tumor infiltrating lymphocytes of cancer tissues and metastatic organs, because a part of alpha-chain of IL-2R is released into the bloodstream on the attachment of IL-2 (interleukin-2) to its specific IL-2R membrane. In most malignant diseases, elevated levels of serum sIL-2R are found, compare to normal control. Serum sIL-2R is a useful parameter for evaluating the disease stage and monitoring the disease progression during the post-treatment follow-up, though it is not an organ-specific parameter.
Male, Receptors, Interleukin-2, Gene Expression Regulation, Neoplastic, Lymphocytes, Tumor-Infiltrating, Neoplasms, Biomarkers, Tumor, Disease Progression, Humans, Interleukin-2, Female
Male, Receptors, Interleukin-2, Gene Expression Regulation, Neoplastic, Lymphocytes, Tumor-Infiltrating, Neoplasms, Biomarkers, Tumor, Disease Progression, Humans, Interleukin-2, Female
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