Homeopathy is an alternative treatment approach that has been widely used for over 200 years. It is popularized as a safe and cost-effective alternative to allopathy. For a holistic approach, homeopathic remedies are used to improve not only patients’ physical condition but also psychological or emotional condition. In dentistry, homeopathy has been used as an adjunct to conventional treatment since 18th century. Many studies indicate that the effect of homeopathic remedies is not different or superior to that of placebo. Institutions such as the World Health Organization and the Food and Drug Administration have not yet approved the ethics and safety of homeopathy as a treatment form. In recent years, regulations on homeopathy by many institutions have been increased, and its prevalence has been limited. Further clinical research is needed to elucidate whether homeopathic remedies can effectively treat conditions that appear to be linked to patients’ spiritual, emotional, mental, and physical conditions, and whether this has a placebo effect. This review aimed to introduce the basics of homeopathy, which has been accepted as part of the Traditional and Complementary Medicine by the Turkish Ministry of Health as of 2016, and to discuss its possible applications in pediatric dental practice.