Ayurveda is attracting global attention due to its holistic approach in the treatment of disease and with minimal adverse drug reaction. Aushadha is very important as it is responsible for alleviation of disease as well as the safeguarding and endorsing wellbeing. Kashaya means distortion of the original form of Dravya and making it suitable for use. Kalpana formulations is a method process of preparation of medicines by using either a single drug or a combination of several drugs. In Ayurveda Panchakarma therapy is used for the maintenance of health and eradication of diseases from their root and Nasya Karma is one among them. Naasa is the gateway toShirasand is the shortest and nearest route to take out the morbid doshas .The Panchavidhakashayakalpanas are Swarasajuice Kalkapaste Shritadecoction Sheetacold infusion and Phanta hot infusion. The usage of these Kalpanas in Nasya karma will be dealt in this article.