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Characterisation of the signalling pathways of the relaxin family peptpide receptors, RXFP1 and RXFP2

Authors: Halls., Michelle Louise;

Characterisation of the signalling pathways of the relaxin family peptpide receptors, RXFP1 and RXFP2

Abstract

Winner of the Mollie Holman Doctoral Medal for Excellence. Two orphan leucine-rich repeat-containing G protein-coupled receptors were recently identified as targets for the relaxin family peptides relaxin and insulin-like peptide (INSL) 3. Relaxin is the cognate ligand for relaxin family peptide receptor (RXFP) 1, whereas INSL3 is the ligand for RXFP2. This study sought to characterise the pharmacological binding properties and signalling pathways of both RXFP1 and RXFP2. This thesis was scanned from the print manuscript for digital preservation and is copyright the author. Author requested conversion to open access 27 Oct 2022

Keywords

Pharmacology and pharmaceutical sciences not elsewhere classified

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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