The reaction of O atoms with l-propanol was studied at pressures of 0.16 to 0.18 Pa, in a fast flow system. O atoms were formed by the reaction of NO with N atoms produced in a microwave discharge through N₂. The temperature dependence of the rate constant over the range 308 to 425 K, gave a pre-exponential factor of (1.7 ± 0.7) x 10⁹ 1 mol⁻¹s⁻¹ and an activation energy of (6 ± 1) kJ mol⁻¹. The relative amounts of propanal formed and 1-propanol reacted were used to obtain absolute rate constants for the reaction and test a reaction mechanism. A similar study was made with 2-propanol in the same fast flow system under similar experimental conditions. The relative amounts of ethanal and 2-propanone formed were measured and used to test a reaction mechanism. The consumption of 2-propanol was also measured and used to obtain absolute rate constants. The temperature dependence of the rate constant over the range 306 to 402 K gave a pre-exponential factor of (4.1 ± 0.5) x 10⁸ 1 mol⁻¹s⁻¹ and an activation energy of (4.0 ± 0.6) kJ mol⁻¹. The results obtained from this study are compared with those obtained from the reaction of O atoms with methanol and ethanol²⁸,²⁹.