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Psicofármacos e VIH

Psychotropic Drugs and HIV
Authors: Moreira, AL; Pereira, M; Telles-Correia, D;

Psicofármacos e VIH

Abstract

Introdução: A infecção VIH/SIDA está muitas vezes associada a perturbações psiquiátricas tais como psicose, depressão e ansiedade. Comorbilidades psiquiátricas podem interferir na adesão à terapêutica anti-retrovírica, pelo que o seu diagnóstico e o tratamento oportuno são essenciais. No entanto, a administração de um psicofármaco concomitante à terapêutica HAART pode resultar em interacções medicamentosas. Objectivos: Esta revisão pretende analisar os vários psicofármacos que podem ser usados nestes doentes, bem como as interacções e reacções adversas que podem surgir. Métodos: Foi efectuada uma pesquisa na literatura anglo-saxónica, de 1993 até 2011, pela MEDLINE, utilizando como palavras-chave: HIV, AIDS, psychosis, depression, anxiety, secondary mania, antidepressive agents, antipsychotics, benzodiazepines, HAART. Resultados: Foram localizados 100 artigos, dos quais 66 foram incluídos e 34 excluídos. Os artigos que não apresentassem dados específicos sobre o uso de psicofármacos nos doentes com VIH foram excluídos. Discussão: Podem ocorrer interações farmacológicas por ocupação das mesmas vias de metabolização dos medicamentos. São necessários estudos adicionais com indicações para uma boa prática clínica. São ainda de considerar as intervenções psicoterapêuticas. Conclusão: A escolha da intervenção terapêutica, nomeadamente quando se consideram psicofármacos, com o menor número de interacções e efeitos adversos é crucial para alcançar o sucesso terapêutico no tratamento dos doentes com VIH.

Psilogos, v. 11, n. 2 (2013)

Country
Portugal
Keywords

Psicofármacos; VIH; Anti-retrovirais; Interações Medicamentosas, Infecção por HIV, Interacção de medicamentos, Antiretrovirais, Antipsicóticos

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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