
Degenerative retinal diseases such as Retinitis Pigmentosa and Age-Related Macular Degeneration are, together, one of the leading causes of blindness in the United States. Retinal prostheses bypass the degenerated cells and apply electrical stimulation directly to the visual neural pathway, creating an artificial sensation of sight in subjects with retinal blindness. Current prostheses utilize a polymer electrode array, which is affixed to the retina using a retinal tack. The electrode array applies mechanical pressure to the retina, which can cause mechanical damage to the very cells which are required to transmit the applied signal. We can mitigate or relocate mechanical damage to the retina through electrode array design changes, but to do so, we must thoroughly understand the mechanical interface between the array and the retina.
Biomedical Engineering (degree program), Viterbi School of Engineering (school), Doctor of Philosophy (degree)
Biomedical Engineering (degree program), Viterbi School of Engineering (school), Doctor of Philosophy (degree)
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