Bloodborne pathogens (BBPs) are the major infectious micro-organisms present in human blood, body fluids and in cuts & wounds which may lead to health hazard and diseases for example - Human Immunodeficiency Virus (HIV), which leads to AIDS; Hepatitis B Virus (HBV), known for causing liver inflammation and chronic disease; and Hepatitis C Virus (HCV), which can result in chronic liver infections. The transmission of the viruses can occur primarily due to contact with infected blood, the injuries due to needlestick, sharps and the sexual contact. Also, the fluids such as blood, semen, vaginal, sweat, saliva however the degree of risk is different. In addition, the transmission can be prevented by using personal protective equipment (PPE), vaccinations (notably for HBV), undergo training on safety protocols, washing the wounds, medical attention. Finally understanding BBPs is also important for preventing health hazards and also adherence to preventive measures which can significantly reduce the risk of transmission in many diverse working environments.