Rajasthan’s eastern region is densely populated and faces a rising burden of chronic kidney disease (CKD), straining the healthcare system. Key nephrology training centers include AIIMS Jodhpur and SMS Medical College, with new facilities opening in Kota and Udaipur State Medical College recently. Renal replacement therapies, such as hemodialysis and deceased donor transplantation, are operational with public and corporate support. Awareness of CKD risk factors and early diagnosis are required to control the disease burden. Enhanced coordination in academic and research activities is necessary to strengthen the healthcare system's response to this growing challenge.