Aim. To assess the adaptive capacity of newborns who have had intrauterine blood transfusions.Materials and methods. The study included 40 newborns who underwent intrauterine intravascular blood transfusion due to hemolytic disease of the fetus RH-factor.Results. The percentage of antenatal fetal losses in hemolytic disease is significantly reduced. Intravascular blood transfusion allowed the fetus to prolong the pregnancy for at least 32 weeks. Survival of newborns with hemolytic disease has significantly increased. Conducting intrauterine blood transfusions leads to a decrease in the frequency and multiplicity of postpartum blood transfusions.Conclusion. With timely delivery and adequate use of high-tech methods of treatment, both intrauterine and postnatal, it is possible in 88% of cases to preserve the life of the newborn with satisfactory rates of physical and neuropsychological development.