
pmid: 32122450
The newborn screen for severe combined immunodeficiency (SCID) uses real-time quantitative polymerase chain reaction for T-cell receptor excision circles and is highly sensitive for SCID. However, T-cell lymphopenia from other primary and secondary causes, such as DiGeorge syndrome, prematurity, thymic involution from stress, and thymectomy during cardiac surgery, is also detected. We present a newborn girl with T-cell lymphopenia of unknown etiology detected via abnormal newborn screen.
Immunosuppression Therapy, T-Lymphocytes, Anti-Inflammatory Agents, Immunologic Deficiency Syndromes, Infant, Newborn, Receptors, Antigen, T-Cell, Infant, Betamethasone, Immunophenotyping, Neonatal Screening, Lymphopenia, Humans, Female, Cells, Cultured, Infant, Premature
Immunosuppression Therapy, T-Lymphocytes, Anti-Inflammatory Agents, Immunologic Deficiency Syndromes, Infant, Newborn, Receptors, Antigen, T-Cell, Infant, Betamethasone, Immunophenotyping, Neonatal Screening, Lymphopenia, Humans, Female, Cells, Cultured, Infant, Premature
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