
We measured amount of tissue kallikrein of gastric mucosa in 39 patients of chronic gastritis by sandwich type enzyme linked immunosorbent assay (S-ELISA) . Amount of tissue kallikrein was 9.1±4.4 ng/g tissue (mean±S.E.) in gastric mucosa of gastric glands, and was about twenty five times as much as it in the parts of atrophic gastric mucosa of them. The quantity of kallikrein was in proportion to age and the extent of atrophic gastritis. It was speculated that tissue kallikrein would participate in inflammatory atrophic change of gastric mucosa in chronic gastritis.
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