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Antimicrobial resistance in bacteria

descriptionPublicationkeyboard_double_arrow_right Article 27 Mar 2009 Belgium English Publisher:Walter de Gruyter GmbHJournal:Open Medicine, volume 4, pages 141-155 (eissn: 2391-5463,

Authors: Bockstael, Katrijn; Van Aerschot, Arthur;

doi: 10.2478/s11536-008-0088-9

Antimicrobial resistance in bacteria

- Summary
- Subjects
- Metrics

Abstract

Abstract The development of antimicrobial resistance by bacteria is inevitable and is considered as a major problem in the treatment of bacterial infections in the hospital and in the community. Despite efforts to develop new therapeutics that interact with new targets, resistance has been reported even to these agents. In this review, an overview is given of the many therapeutic possibilities that exist for treatment of bacterial infections and how bacteria become resistant to these therapeutics.

Country

Belgium

Related Organizations

Rega Institute for Medical Research
Belgium
Katholieke Universiteit Leuven
Belgium
KU Leuven
Belgium

Keywords

FLUOROQUINOLONES, target sites, Alteration of drug target, antimicrobial agents, drug discovery, MECHANISMS, Efflux, Resistance development, Medicine, General & Internal, QUINOLONES, General & Internal Medicine, gram-positive cocci, GRAM-POSITIVE COCCI, MODE, fluoroquinolones, TARGET SITES, tetracycline, antibacterials, mechanisms, Science & Technology, beta-lactam antibiotics, R, mode, Antimicrobial agents, efflux, DRUG DISCOVERY, alteration of drug target, GLYCOPEPTIDE ANTIBIOTICS, Antibacterials, BETA-LACTAM ANTIBIOTICS, Medicine, quinolones, glycopeptide antibiotics, Life Sciences & Biomedicine, TETRACYCLINE, resistance development

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	68
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%