Maternal mortality has posed a great problem in the health sector of most African countries. Nigeria’s maternal mortality ratio remains high despite efforts made to meet millennium development goal 5 (MDG5). This study used the Lagos state community health survey 2011 and the Lagos state health budget allocations 2011 to examine the effect of government expenditure on maternal mortality ratio. Factors like inadequate transportation facilities, lack of awareness, inadequate infrastructures, which contribute to high maternal mortality rate, can be traced back to revenue though under different ministries. The other ministries need to work and support the ministry of health in the fight against maternal, especially in Lagos state. Secondary data was compiled from the state budget, records of death in different local governments in the state and relevant reviewed literature. Regression analysis was used to analyze the hypothesis and it was discovered that government expenditure does not have a significant effect on maternal mortality based on the R-square coefficient. However, correlation coefficient gives a contrasting result. Hence, further research work, government expenditure from other local government areas need to be taken into consideration to arrive at a valid conclusion. It is difficult to ascertain how much of the revenue allocated was put to appropriate use, due to a high level of corruption.