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Journal of Cardiac Arrhythmias
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Journal of Cardiac Arrhythmias
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Journal of Cardiac Arrhythmias
Article . 2020
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Journal of Cardiac Arrhythmias
Article . 2020
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Journal of Cardiac Arrhythmias
Article . 2020
Data sources: DOAJ
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Evaluation of Tpeak–Tend and QT intervals in Chagas’ Disease, Chronic Phase and Normal Electrocardiogram

Authors: Abilio Augusto Fragata Filho; Claudia da Silva Fragata; Angela Maria Lourenço; Cristiane Castro Faccini; João Ítalo Dias França;

Evaluation of Tpeak–Tend and QT intervals in Chagas’ Disease, Chronic Phase and Normal Electrocardiogram

Abstract

Introduction: Chagas’ disease lacks elements to predict which carriers will evolve into cardiac form and which will remain in undetermined form. Objective: To evaluate the relationship between electrocardiographic evolution and Tpeak–Tend and QT intervals, both corrected for heart rate, in chagasic patients with normal initial electrocardiogram. Method: Chagasic patients admitted to the institution until 2002 were retrospectively evaluated, and the electrocardiogram was normal at the first consultation. The Tpeak–Tend and QT intervals were measured in milliseconds at the V2 and V5 derivations, with the mean values corrected for heart rate (Bazett). The relationship of these values with the electrocardiographic evolution of the individuals was analyzed, considering the gender, time of evolution and whether they received benznidazole or not. Results: The corrected Tpeak–Tend interval showed no statistical significance among those who maintained or not normal electrocardiogram. The corrected QT interval, the treatment with benznidazole and the time of evolution showed significance for the maintenance of normal electrocardiogram. In the multivariate evaluation, treatment with benznidazole, the QTc interval and the time of evolution were independent variables for the maintenance of normal electrocardiogram. Conclusion: The Tpeak–Tend interval showed no predictor of electrocardiographic evolution. The increased QT interval favored changes.

Keywords

Chagas’ disease, QT interval, RC666-701, Diseases of the circulatory (Cardiovascular) system, Tpeak–Tend interval

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold