Bone Age Corresponds With Chronological Age at Type 1 Diabetes Onset in Youth
Copyright policy )Bone Age Corresponds With Chronological Age at Type 1 Diabetes Onset in Youth
OBJECTIVE To our knowledge, only two controversial articles have reported the study of bone age at diagnosis in diabetic children. The aim of this study was to compare chronological age with bone age and to evaluate the impact of A1C on bone age in children at diagnosis of type 1 diabetes. RESEARCH DESIGN AND METHODS In 496 diabetic children, height was measured at diagnosis and height SD score was calculated using the British 1990 growth reference. Bone age was determined according to the Greulich and Pyle method, and A1C levels were measured. RESULTS Participants' height was normal for age and sex. No significant differences were found between chronological age and bone age, and there was no correlation between Δ (bone age − chronological age) and A1C. CONCLUSIONS This study showed that height and bone maturation among diabetic children are normal for age and sex and independent of A1C at diagnosis of type 1 diabetes.
- Université Libre de Bruxelles Belgium
- Queen Fabiola Children's University Hospital Belgium
- Boston Children's Hospital United States
Glycated Hemoglobin, Male, Adolescent, Infant, Sciences bio-médicales et agricoles, Body Height, Diabetes Mellitus, Type 1, Reference Values, Age Determination by Skeleton, Child, Preschool, Humans, Female, Child, Original Research
Glycated Hemoglobin, Male, Adolescent, Infant, Sciences bio-médicales et agricoles, Body Height, Diabetes Mellitus, Type 1, Reference Values, Age Determination by Skeleton, Child, Preschool, Humans, Female, Child, Original Research
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