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Immunotoxicology in the Pharmaceutical Industry

Name: Immunotoxicology in the Pharmaceutical Industry
Creator: Kenneth C. Norbury
Keywords: Drug Industry, Drug Evaluation, Preclinical, Immunity, Immunoglobulins, 04 agricultural and veterinary sciences, Lymphocyte Activation, Toxicology, Rats, 3. Good health, 0403 veterinary science

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 1982Publisher:JSTORJournal:Environmental Health Perspectives, volume 43, page 53 (issn: 0091-6765,

Authors: Kenneth C. Norbury;

doi: 10.2307/3429168 , 10.1289/ehp.824353

pmid: 7037389

pmc: PMC1568893

Immunotoxicology in the Pharmaceutical Industry

- Summary
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Abstract

Development of an immunotoxicology program within the pharmaceutical industry is described. With few guidelines in the area and a multitude of factors to consider, a basic screen for evaluating immune competence in species routinely used in toxicologic studies has been proposed. The future of immunotoxicology depends upon the ability of the selected immune function tests to be predictive of human risk.

Keywords

Drug Industry, Drug Evaluation, Preclinical, Immunity, Immunoglobulins, Lymphocyte Activation, Toxicology, Rats, Mice, Immunologic Techniques, Animals, Cyclophosphamide, Immunocompetence, Immunosuppressive Agents

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	13
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average