1. Methods for hybridizing Fundulus heteroclitus and Scomber scombrus are described.2. The pigment development in hybrid and parents is described.3. Comparison of the inheritance of embryo and yolk melanophores reveals a Scomber-effect in the embryo.4. The hybrid embryo shows chromatophore inheritance from both parents.5. Actually, as regards inheritance of melanophores and chromatophores, there is enormous variability, no two embryos being identical as to pigment distribution.6. This variation in the F1 generations is unusual and at present inexplicable.