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Treatment of hepatorenal syndrome

Authors: Kezić Aleksandra; Mijač Dragana; Stojimirović Biljana;

Treatment of hepatorenal syndrome

Abstract

<zakljucak> Hepatorenalni sindrom je funkcionalna insuficijencija bubrega u sklopu terminalne insuficijencije jetre. U patogenezi ovog sindroma ucestvuju hemodinamske promene (snizeni srednji arterijski pritisak i perfuzioni pritisak bubrega) i povecano stvaranje sistemskih i bubreznih vazoaktivnih medijatora sa stimulacijom bubreznog simpatickog sistema. Standardna medicinska farmakoloska terapija usmerena je na prethodno navedene patofizioloske poremecaje. U poslednje vreme postupci detoksikacije, npr. jedan od vidova albuminske dijalize, pojavljuju se sve vise u lecenju bolesnika sa HRS, ali se jos ne preporucuju kao standardna procedura. Oba vida lecenja preduzimaju se samo kao premoscenje perioda do transplantacije jetre ili u slucajevima kada se ocekuje oporavak funkcije jetre, jer bubrezna funkcija direktno zavisi od funkcije jetre. Standardna hemodijaliza ne pomaze u poboljsanju funkcije bubrega. Jedino kauzalno resenje ovog problema donosi transplantacija jetre.

Keywords

Medicine (General), Hepatorenal Syndrome, liver transplantation, portasystemic shunt transjugular intrahepatic, vasoconstrictor agents, drug therapy, R5-920, treatment outcome, dialysis, Humans, hepatorenal syndrome

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold