Proponents of bilaterally balanced occlusion believe that this occlusal concept is important for denture retention and stability. However, the critical appraisal of the literature reveals no scientific evidence to support the bilaterally balanced occlusion as the ideal occlusal concept for conventional complete dentures. Current evidence suggests that the occlusal concept has little influence on clinical outcomes or patient satisfaction. Additional randomized controlled clinical trials should be developed taking into account the influence of mucosal resiliency, alveolar ridge anatomy, and parafunctional activities on occlusal concept choice. In this paper, various types of complete denture occlusion (bilaterally balanced occlusion, lingualized occlusion, canine-guided occlusion) will be reviewed and compared.