We examined how occupational self-efficacy is related to organizational commitment, and how it indirectly influences work engagement. Participants were 328 part-time Master of Business Administration students in China. We used structural equation modeling and chi-square difference tests to analyze the data and assess the proposed mediating effect. Results showed that occupational self-efficacy had a direct effect on organizational commitment and an indirect effect on work engagement through the mediator of organizational commitment. Our findings extend previous results and show that occupational self-efficacy can be used to predict work engagement.