This paper presents an overview of extensive set fatigue tests results in low-cycle domain carried out at the Department of Applied Mechanics at the VŠB – Technical University of Ostrava on smooth specimens made of 2124T851 aluminum alloy. Overall, results of 24 tests of the aforementioned type under proportional loading and 40 tests under non-proportional loading with various strain path shapes were evaluated within the FADOFF project (Fatigue Analysis Documentation Office) supported by the Technology Agency of the Czech Republic. All tests were realized under the zero mean strain at the room temperature. Investigated aluminum alloy has exhibited in the torsion tests significantly shorter lifetime than under the tension-compression symmetrical loading at the same level of equivalent strain amplitude. The experimental set was realized in order to validate low-cycle fatigue criteria in a future work.