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Revista Digital Universitaria
Article . 2019 . Peer-reviewed
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Epigénesis: secuelas de una infancia adversa

Authors: Gonzalez Salinas, Sofia; Sánchez Moguel, Sergio Manuel; Ramírez Jiménez, Nelida;

Epigénesis: secuelas de una infancia adversa

Abstract

El maltrato infantil es un problema de salud pública a nivel mundial cuyas secuelas a largo plazo han sido poco descritas. Diversos estudios demuestran que una infancia adversa predispone al desarrollo de enfermedades cardiovasculares, metabólicas, inmunológicas y psiquiátricas en la edad adulta. Pero ¿cuál es el mecanismo que permite observar estos cambios patológicos varias décadas después de que ocurrieron los eventos adversos? Una posible respuesta reside en las modificaciones epigenéticas del genoma de las células, las cuales influyen en la expresión de la información hereditaria sin alterar la secuencia de nucleótidos del genoma. Los estudios más recientes sugieren que los cambios en la metilación del material genético son uno de los mecanismos epigenéticos a través del cual las historias de maltrato dejan huellas en la salud física y emocional del adulto.

Country
Italy
Keywords

General Medicine

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
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