Lysyl Oxidase in Cancer Research

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 2014 Denmark English Publisher:Informa UK LimitedJournal:Future Oncology, volume 10, pages 1,709-1,717 (issn: 1479-6694, eissn: 1744-8301,

Copyright policy )Funded by:NNF | unidentified

Authors: Perryman, Lara; Erler, Janine Terra;

doi: 10.2217/fon.14.39

pmid: 25145437

Lysyl Oxidase in Cancer Research

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Abstract

Metastasis is the main reason for cancer-associated deaths and therapies are desperately needed to target the progression of cancer. Lysyl oxidase (LOX) plays a pivotal role in cancer progression, including metastasis, and is therefore is an attractive therapeutic target. In this review we will breakdown the process of cancer progression and the various roles that LOX plays has in the advancement of cancer. We will highlight why LOX is an exciting therapeutic target for the future.

Country

Denmark

Related Organizations

University of Copenhagen
Denmark
University of Copenhagen
Denmark

Keywords

Protein-Lysine 6-Oxidase, Biomedical Research, Neoplasms, Tumor Suppressor Proteins, Animals, Humans, Neoplasm Metastasis, Protein Processing, Post-Translational

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