<script type="text/javascript">
<!--
document.write('<div id="oa_widget"></div>');
document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=undefined&type=result"></script>');
-->
</script>

COPY SCRIPT

For further information contact us at helpdesk@openaire.eu

Telithromycin in Lower Respiratory Tract Infections

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 2006 Italy Publisher:Informa UK LimitedJournal:Future Microbiology, volume 1, pages 7-16 (issn: 1746-0913, eissn: 1746-0921,

Authors: F. Blasi; M. Cazzola; P. Tarsia; S. Aliberti; C. Baldessari; V. Valenti;

doi: 10.2217/17460913.1.1.7

pmid: 17661681

handle: 2434/437986 , 10281/20962

Telithromycin in Lower Respiratory Tract Infections

- Summary
- Subjects
- Metrics

Abstract

Telithromycin is a ketolide, a semisynthetic derivative of the 14-membered ring macrolide antibiotics, with an expanded spectrum of activity relative to macrolides. Its good tissue pharmacokinetic characteristics allows once-daily administration, and it has been successfully employed in lower respiratory tract infections. Recent data indicate that telithromycin may exert anti-inflammatory/immunomodulatory effects that may be of use in the treatment of both acute and chronic airway diseases. This review examines the role of telithromycin in lower respiratory tract infections, analyzing published data on exacerbations of chronic bronchitis, community-acquired pneumonia and asthma in adults. In addition, pharmacokinetic and pharmacodynamic properties of the drug are considered.

Country

Italy

Related Organizations

University of Milano-Bicocca
Italy
University of Milan
Italy

Keywords

Adult, Ketolides, Asthma; Community-Acquired Infections; Pneumonia; Bronchitis, Chronic; Adult; Ketolides; Anti-Bacterial Agents; Humans, Pneumonia, Asthma, Anti-Bacterial Agents, Bronchitis, Chronic, Community-Acquired Infections, acute exacerbations of chronic bronchitis; asthma; community-acquired pneumonia; telithromycin, Humans

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	4
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average