Sugar mill effluents are responsible for deterioration of water quality, due to effluents physical and chemical characteristics of river water changes and become unfit for human consumption. The present study was undertaken on the physico-chemical parameters of Bhima-Patas sugar industry effluent in Daund Tahsil. The study was conducted during 2009-2012 in crushing season of sugar industry. During the study period we recorded the different Physical as well as chemical properties of sugar mill effluent like Temperature, pH, TSS, TDS, Hardness, BOD, COD, DO, SO4, PO4, Oil and Grease, Zn, Hg etc. The result from the analysis of sugar industry waste water (effluent) shows that most of the parameters were much higher than the Minimum Pollution Level (MPL). Hence the flow of this effluent into the river causes serious pollution problems for aquatic life as well as human and livestock.