Introduction: Pyogenic granuloma is a pseudo-tumor which has a great tendency to attached gingiva. Conservative surgery is a treatment choice for this lesion. Among different laser wavelengths used for oral surgery including CO2, Nd:YAG, Erbium family and diode laser, diode can be the best option due to providing blood less area that make better view for surgeon to remove it completely. Case Report: A 14-year-old girl with a chief complaint of exophytic lesion in lower jaw was referred. The surgery was done by 980 diode laser with output power of 1 W in continuous mode. The lesion was sent to pathology laboratory for further investigation. The patient was advised to keep oral hygiene instructions. Results: After 1 weeks, complete healing was observed. Conclusion: Diode laser can be a treatment choice for this kind of lesions due to diminished infection and bacteremia following surgery, reduction of relapse and bone degeneration, less invasive technique and reduced chair time.