AbstractAnti‐microbial drug resistance (AMR or AMDR) is a complex multi‐dimensional and systemic failure in health education, social behavior, health care legislation and/or policies and practices. AMDR is a life threatening infection extending beyond national boundaries. Collaboration among the health care, pharmaceutical, agricultural and consumer communities is a prerequisite to ward off this unraveling human made pandemic. Education of stakeholders, proper hygiene practices, infection prevention and responsible antibiotic “stewardship” are essential strategic elements of remedial and preventive programs.