The system used to classify soils based on their FCC fertility groups the soils of the Ríos de Tabasco sub-region (SRT) according to parameters of the superior soil layer, and some characteristics of the subsoil linked to the growth of palm oil (Elaeis guineensis Jacq.). A soil study of 361,855.9 ha was performed to decide the expansion of the area cultivated with palm oil, classifying the fertility of the SRT soils to improve decision making. The factors that limit the potential of the SRT soils for their agricultural and livestock use were acidity, water excess or deficit, clay content, erosion, nutrient deficiencies, presence of Na, alkalinity and low CIC which, alone or grouped, have an influence on the detriment of soil fertility. Agricultural drainage, whitewashing, irrigation and fertilization with macro and micro nutrients, can be agronomic practices that would allow improving the conditions of the Gleysol, Vertisol, Fluvisol and Acrisol units for palm oil. The rest of the subunits must be conserved with natural vegetation, to conserve their role of buffer and moisture retention zones. To solve these problems, an integral analysis is required which takes into account the type of crop, time of sowing, and availability of technology.