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Asthma Allergy Immunology
Article . 2016 . Peer-reviewed
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Asthma Allergy Immunology
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Risk Grup in Anaphylaxis: Infant Anaphylaxis

Anafilakside Riskli Grup: İnfant Anafilaksisi
Authors: Erdem, Semiha Bahçeci; Karaman, Sait; Nacaroğlu, Hikmet Tekin; Karkıner, Canan Şule Ünsal; Kanık, Esra Toprak; Nalçabasmaz, Tugba; Yazıcı, Selçuk; +1 Authors

Risk Grup in Anaphylaxis: Infant Anaphylaxis

Abstract

Objective: The infantile group that is accepted to be at risk of anaphylaxis has a special importance since they are unable to express their complaints and also the signs and symptoms of anaphylaxis can be confused with common symptoms of infants such as drooling, vomiting, diarrhea and itching. However, early detection of the signs and symptoms of anaphylaxis is crucial for effective diagnosis and treatment. The aim of study was to draw attention to infants anaphylaxis.Materials and Methods: All of the patients in the infant group (n=15) among a total of 35 anaphylaxis cases that we followed in the Pediatric Allergy Clinic of Dr. Behçet Uz Children's Hospital between the years 2011-2015 were included in the study. Demographic and clinical features of the patients were evaluated.Results: 9 of 15 (60%) patients involved in the study were male and 6 (40%) were female, and the average age of anaphylaxis was 8.13±6.83 (min 1-max 24) months. In 93% of cases (n=14) the trigger was food and in 7% of cases (n=1) the trigger was not determined. The most frequently responsible foods were respectively cow's milk (67%) and egg (20%). In 7 patients (47%), there were respiratory system and skin manifestations, in 7 patients (47%) 3 system involvement and in 1 patient respiratory and gastrointestinal system involvement has been observed. In only 3 cases (20%) the blood pressure was measured and also epinephrine was administered to only 3 cases (20%) in the hospital. In only 3 of the patients (20%), an epinephrine injector was prescribed after anaphylaxis. Conclusion: It was detected that the most common triggers are cow's milk and egg, the subjective symptoms are frequently overlooked, an atopic nature is a risk factor and physicians' rates of blood pressure measurement, epinephrine administration and EpiPen autoinjector prescription are low.

Giriş: Anafilaksi açısından riskli kabul edilen infantil grup, hem yakınmalarını ifade edemediği için, hem de anafilaksi semptom ve bulguları infanttaki salya akması, kusma, ishal, kaşınma gibi sık görülen bulgularla karışabildiği için özel bir öneme sahiptir. Oysa ki anafilakside semptom ve bulguların erken saptanması efektif tanı ve tedavi için çok kritiktir. Çalışmada amacımız infant anafilaksilerine dikkat çekmektir.Gereç ve Yöntem: Çalışmaya 2011-2015 yılları arasında Dr. Behçet Uz Çocuk Hastanesi Çocuk Allerji Kliniği'mizde takip ettiğimiz toplam 35 anafilaksi içinden infant grubunda olanların tümü (15 olgu) alınmıştır. Olguların demografik ve klinik bulguları değerlendirilmiştir.Bulgular: Çalışmaya alınan 15 hastanın 9'u (%60) erkek, 6'sı (%40) kız olup ortalama anafilaksi görülme yaşı 8,13±6,83 (min 1-max 24) aydır. Olguların %93'ünde (n=14) tetikleyicinin besin olduğu, %7 olguda (n=1) tetikleyicinin saptanamadığı belirlenmiştir. En sık sorumlu besin sırasıyla inek sütü (%67) ve yumurta (%20) dır. Olguların 7'sinde (%47) solunum sistemi ve deri bulgusu, 7'sinde (%47) 3 sistem tutulumu, 1 hastada ise solunum ve GIS tutulumu gözlenmiştir. Olguların sadece 3'ünün (%20) kan basıncı ölçülmüş, 3'üne (%20) hastanede epinefrin uygulanmıştır. Hastalardan sadece 3'üne (%20) anafilaksi sonrası epinefrin hazır enjektör reçete edilmiştir. Anafilaksi bir hastada 2 kez, bir diğer hastada da 4 kez tekrarlamıştır.Sonuç: En sık tetikleyicinin inek sütü ve yumurta olduğu, subjektif semptomların genellikle gözden kaçtığı, atopik yapının risk faktörü olduğu ve kan basıncı ölçme, epinefrin uygulama, epipen otoenjektörü reçeteleme oranlarımızın düşük olduğu saptanmıştır.

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Keywords

İmmünoloji, Infant, Yumurta, Cow's Milk, Food Allergy, Anaflaksi, Besin Allerjisi, İnek Sütü, Egg, Anaphylaxis, İnfant

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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