The use of adequate plant density in combination with the amino acid application can play a decisive role in achieving optimal yields in sesame crops. In order to evaluate the effects of the influence of plant densities and the application of amino acids on the growth and yield of sesame seeds in the rainy season, an experiment was carried out between June and October 2023. Three doses of amino acids (AV) were examined: without VA, 0.25 and 0.50 L ha-1 and two plant densities (25,000 and 29,000 plants/ha), distributed in Split-plots, in a randomized block design with three replications. The results showed that plant densities influence the growth and yield of the sesame crop, the density of 25,000 plants ha-1 influenced the number of plant leaves, leaf area and the AF/NH ratio, while the density of 29,000 plants ha-1 showed greater plant height and yield. Additionally, the dose of 0.25 L ha-1 promoted the growth of sesame plants at the density of 25,000 plants/ha and a higher yield at the density of 29,000 plants/ha, while the dose of 0 .50 L ha-1 of amino acids showed greater productivity at the density of 25,000 plants/ha. The results of this study suggest that the use of high plant densities in combination with the foliar application of amino acids is an viable strategy to increase sesame productivity in the rainy season.