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Japanese Journal of Clinical Immunology
Article . 2007 . Peer-reviewed
Full-Text: http://www.jstage.jst.go.jp/article/jsci/30/5/30_5_369/_pdf
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Japanese Journal of Clinical Immunology
Article . 2007 . Peer-reviewed
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Japanese Journal of Clinical Immunology
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Japanese Journal of Clinical Immunology
Article . 2008
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https://dx.doi.org/10.2177/jsc...
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Therapeutic potential of phosphoinositide 3-kinase inhibitors in rheumatoid arthritis

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2007 English Publisher:Japan Society for Clinical ImmunologyJournal:Japanese Journal of Clinical Immunology, volume 30, pages 369-374 (issn: 0911-4300, eissn: 1349-7413, Copyright policy )
Authors: TAMURA, Naoto; HARUTA, Kazuhiko;

doi: 10.2177/jsci.30.369

pmid: 17984576

Therapeutic potential of phosphoinositide 3-kinase inhibitors in rheumatoid arthritis

Abstract

Activation of PI3K is a key step of intracellular signaling involved in many cellular functions. PI3K inhibitors have shown anti-rheumatic effects on arthritis model in mice. PI3K is a potential therapeutic target of rheumatoid arthritis.

Related Organizations
Keywords

Phosphoinositide-3 kinase (PI3K), rheumatoid arthritis, therapy, PI3K inhibitor, Arthritis, Rheumatoid, Phosphatidylinositol 3-Kinases, Quinoxalines, Animals, Humans, Thiazolidinediones, ZSTK474, Phosphoinositide-3 Kinase Inhibitors

  • BIP!
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    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 1
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
gold