Ayurveda, the science of life is being practised by Aryans from Vedic period. Kalpana is the process through which a substance transformed into different medicine form according to the need. In Rasashastra almost all the drugs are advised to be processed with specific Shodhana process before their internal uses. Shodhana, which literally means purification and converting drug fit for further procedure. Hence, the Shodhana process is aimed to remove impurities present in the drugs. Shodhana procedure is necessary for every drug before taking it for adding in any compound or subjecting it for further processes. After Shodhana process the drug - Physical, Chemical and biological changes take place, which are required for proper therapeutic action of the end product.