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Thrombolysis for Acute Ischemic Stroke

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2009 Belgium English Publisher:Bentham Science Publishers Ltd.Journal:Current Topics in Medicinal Chemistry, volume 9, pages 1,285-1,290 (issn: 1568-0266,

Authors: Uyttenboogaart, M; De Keyser, Jacques; Luijckx, G.j.;

doi: 10.2174/156802609789869655

pmid: 19849662

handle: 20.500.14017/35b565f4-c6c6-4aeb-92bb-130fb4d62865

Thrombolysis for Acute Ischemic Stroke

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Abstract

In the last decennium, thrombolytic therapy has changed the management of acute ischemic stroke. Randomized clinical studies have demonstrated that intravenous thrombolysis with tissue plasminogen activator improves functional outcomes. Recently the time window for intravenous thrombolysis has been extended from 3 to 4.5 hours after stroke onset, which will allow more stroke patients to benefit from this treatment. Currently several studies are investigating how to improve recanalization rates of thrombolytic therapy. In this review several aspects of intravenous and intra-arterial thrombolysis are discussed.

Country

Belgium

Related Organizations

Universitair Ziekenhuis Brussel
Belgium
Université Libre de Bruxelles
Belgium
University of Groningen
Netherlands
Vrije Universiteit Brussel
Belgium
University Medical Center Groningen
Netherlands

Keywords

Stroke, thrombolysis, acute ischemic stroke, Clinical Trials as Topic, Fibrinolysis, Tissue Plasminogen Activator, Humans, Thrombolytic Therapy, Brain Ischemia

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	9
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average