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Plant-derived Terpenoids and Analogues as Anti-HIV Agents

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2003Publisher:Bentham Science Publishers Ltd.Journal:Current Topics in Medicinal Chemistry, volume 3, pages 155-169 (issn: 1568-0266,

Authors: Susan L. Morris-Natschke; I-Chen Sun; Yoshiki Kashiwada; Kuo Hsiung Lee;

doi: 10.2174/1568026033392435

pmid: 12570771

Plant-derived Terpenoids and Analogues as Anti-HIV Agents

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Abstract

The plant-derived terpenoids and analogues are reviewed with respect to their anti-HIV activity, structure-activity relationships, and mechanism of action. The active compounds include diterpenoid lactones, phenolic diterpenes, atisane and kaurane diterpenes, phorbol diterpenes, triterpene glycosides, friedelane triterpenes, taraxerane triterpenes, ursane triterpenes, lanostane triterpene, lupane triterpenes, seco-ring A triterpenes, degraded triterpenes, and cucurbitacin triterpenes. Positive new leads for drug development will be highlighted.

Related Organizations

University of North Carolina at Chapel Hill
United States

Keywords

Anti-HIV Agents, Terpenes, Plants

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	55
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%