Oligonucleotides and Oligonucleotide Conjugates: A New Approach for Cancer Treatment

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2005 English Publisher:Bentham Science Publishers Ltd.Journal:Current Medicinal Chemistry, volume 12, pages 71-88 (issn: 0929-8673,

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Authors: DA ROS, TATIANA; SPALLUTO, GIAMPIERO; PRATO, MAURIZIO; SAISON BEHMOARAS T; BOUTORINE A; CACCIARI B.;

doi: 10.2174/0929867053363603

pmid: 15638731

handle: 11368/1693541 , 11392/1198404

Oligonucleotides and Oligonucleotide Conjugates: A New Approach for Cancer Treatment

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Abstract

In this account we summarise recent studies on oligonucleotides and oligonucleotide derivatives and their utilisation in antigene, antisense and decoy approaches, with particular attention to peptide nucleic acids, locked nucleic acids and oligonucleotide conjugates, the most promising compounds in this field.

Related Organizations

University of Trieste
Italy
University of Ferrara
Italy

Keywords

Molecular Conformation, Oligonucleotides, Antineoplastic Protocols, Oligonucleotides, Antisense, Cross-Linking Reagents, Neoplasms, Nucleic Acids, ", "; oligonucleaotide, Humans, oligonucleaotide

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