Wavefront Coding has been applied as a means to increase the effective depth of focus of optical systems. In this note I discuss the potential for this technique to increase the depth of focus of the LSST and the resulting advantages for the construction and operation of the facility, as well as possible drawbacks. It may be possible to apply Wavefront Coding without changing the current LSST design, in which case Wavefront Coding might merit further study as a risk mitigation strategy.