Nuclear medicine and imaging research (quantitative studies in radiopharmaceutical science)
Nuclear medicine and imaging research (quantitative studies in radiopharmaceutical science)
This report describes three studies aimed at using radiolabeled pharmaceuticals to explore brain function and anatomy. The first section describes the chemical preparation of (F18)fluorinated benzamides (dopamine D-2 receptor tracers), (F18)fluorinated benzazepines (dopamine D-1 receptor tracers), and tissue distribution of (F18)-fluoxetine (serotonin reuptake site tracer). The second section relates pharmacological and behavioral studies of amphetamines. The third section reports on progress made with processing of brain images from CT, MRI and PET/SPECT with regards to brain metabolism of glucose during mental tasks.
- University of North Texas United States
- University of Chicago United States
Central Nervous System, Distribution, Nervous System, Hydroxy Compounds, Isotopes, Cerebellum, Tissue Distribution, Amines, Mammals, 59 Basic Biological Sciences, Cerebral Cortex, Chromatography, Radiochemistry, Organic Compounds, Isomeric Transition Isotopes, Drugs, Brain, 551001 -- Physiological Systems-- Tracer Techniques, 550101 -- Behavioral Biology-- Tracer Techniques, Separation Processes, Neuroregulators, Man, Autonomic Nervous System Agents, Body, 62 Radiology And Nuclear Medicine, Fluorine Isotopes, Beta Decay Radioisotopes, 400703 -- Radiochemistry & Nuclear Chemistry-- Radioisotope Production, 38 Radiation Chemistry, Liquid Column Chromatography, Phenols, Nanosec Living Radioisotopes, Chemical Preparation, Animals, Light Nuclei, Cardiotonics, Behavior, Progress Report, Structure-Activity Relationships, Membrane Proteins, Proteins, Polyphenols, Document Types, Amides, Labelled Compounds, Rats, Aromatics, Hours Living Radioisotopes, Radiopharmaceuticals, And Nuclear Chemistry
Central Nervous System, Distribution, Nervous System, Hydroxy Compounds, Isotopes, Cerebellum, Tissue Distribution, Amines, Mammals, 59 Basic Biological Sciences, Cerebral Cortex, Chromatography, Radiochemistry, Organic Compounds, Isomeric Transition Isotopes, Drugs, Brain, 551001 -- Physiological Systems-- Tracer Techniques, 550101 -- Behavioral Biology-- Tracer Techniques, Separation Processes, Neuroregulators, Man, Autonomic Nervous System Agents, Body, 62 Radiology And Nuclear Medicine, Fluorine Isotopes, Beta Decay Radioisotopes, 400703 -- Radiochemistry & Nuclear Chemistry-- Radioisotope Production, 38 Radiation Chemistry, Liquid Column Chromatography, Phenols, Nanosec Living Radioisotopes, Chemical Preparation, Animals, Light Nuclei, Cardiotonics, Behavior, Progress Report, Structure-Activity Relationships, Membrane Proteins, Proteins, Polyphenols, Document Types, Amides, Labelled Compounds, Rats, Aromatics, Hours Living Radioisotopes, Radiopharmaceuticals, And Nuclear Chemistry
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